CERTaIN: CER/PCOR Methods: Introduction

In this course, you will be introduced to basic statistics and study designs used in CER/PCOR and the ethical considerations to take into account when conducting CER/PCOR.

This introductorycourse includes 4 lectures:

1. Basic Statistics for PCOR/CER I
2. Basic Statistics for PCOR/CER II
3. Ethics
4. Introduction to Comparative Effectiveness and Patient-Centered Outcomes Research

This course is intended for anyone interested in CER/ PCOR methods.

This course is supported by grant number R25HS023214 from the Agency for Healthcare Research and Quality.

Basic Statistics for PCOR/CER I

• Sampling methods
• Stratification and controlling for bias and confounding
• Study power
• Sample size
• Common study designs

Basic Statistics for PCOR/CER II

• Types of data
• Parametric and non-parametric measures
• Relationship between sample size and standard deviation
• Odds ratios and relative risks
• P-values and confidence intervals

Ethics

• Seven principles of research ethics and their application to CER/PCOR
• History of ethics in research

Introduction to Comparative Effectiveness and Patient-Centered Outcomes Research

• Examples of CER/PCOR
• CER vs. randomized controlled trials
• Patient-centered outcomes Research Institute (PCORI)