Biology

NMR spectroscopy for Chemists and Biologists

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This course will start with Basic principles of NMR, walk through the analysis of spectra and demonstrate the application of multidimensional NMR spectroscopy in Chemistry and structural Biology.INTENDED AUDIENCE: M. Sc./ PhD and Scientists working in Pharma and Biophrma IndustriesPREREQUISITES: Under graduate level understanding of Physics and MathematicsINDUSTRY SUPPORT: Biocon, Wockhardt, Aurobindo Biopharma etc

Molecular Biology

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The current core course has been specifically planned for the students studying in the arena of Zoology subject at College or University level as per the UGC approved curriculum. In addition, this particular core course can also be adopted by undergraduate students studying in the relevant disciplines of Biological Sciences encompassing Life-Science, Biochemistry, Biotechnology, Genetics, Biomedical Technology, Forensic Science, Pharmaceutical Sciences, Cancer Biology, Clinical Research, Microbiology, Bioinformatics, Paramedical as well as Medical fields.The present core course has been organized magnificently to cover all the essential aspects related to Molecular Biology field. The course will provide a brief overview of Nucleic acid background comprising of salient features and models of DNA and RNA. The course will mainly focus on the study of principal molecular events of cell incorporating DNA Replication, Transcription and Translation in prokaryotic as well as eukaryotic organisms. The course will also emphasize Post Transcriptional Modifications and Processing of Eukaryotic RNA covering the concepts of Split genes, Introns, Exons, Splicing Mechanisms and RNA Editing. The course will also impart detailed explanation of Prokaryotic and Eukaryotic Transcriptional Regulation along with mechanism of Gene Silencing. During this course, the students will be imparted comprehensive understanding about key concept of DNA Repair Mechanisms. In addition, the course will provide glimpse of Ribo-switches, RNA Interference, miRNA and siRNA as a part of different types of Regulatory RNAs. The course will also provide the additional knowledge regarding various aspects of molecular biology in the form of supplementary study material.Course Objectives:The structure of the present core course on Molecular Biology has been magnificently designed with the perspective to achieve following key objectives:To provide comprehensive background of Salient features of Nucleic Acids and DNA model to the course learners.To impart detailed understanding of key events of molecular biology comprising of mechanism of DNA Replication, Transcription and Translation in Prokaryotes and Eukaryotes.To provide adequate knowledge about Post Transcriptional Modifications andProcessing of Eukaryotic RNA to the course learners.To give detailed explanation of Transcriptional Regulation with examples of lac operon and tryptophan operon in prokaryotic as well as eukaryotic organisms along with key concept of Gene Silencing to the course learners.To develop comprehensive understanding regarding DNA Repair Mechanisms in the course learners.To provide glimpse of types of Regulatory RNAs by imparting adequate informationabout Ribo-switches, RNA Interference, miRNA and siRNA to the course learners.Eligibility forEnrollment:Thosestudentswho have passed(10+2)withBiological Sciencesubject with at least55% marksand/or at present studying Zoology at undergraduate level.Course Pre-requisite:Pre-requisite for admission in this course will be(10+2)with anyBiological Sciencewith at least55% marks.Intended Audience:The course has been intended for thestudents studying in the arenas of relevant biological science disciplines encompassing Life-Science, Biochemistry, Biotechnology, Genetics, Bioinformatics, Microbiology, Forensic Science, Environmental Science, Biomedical Technology, Cancer Biology, Clinical Research, Pharmaceutical Sciences, Cancer Biology, Medical Science and Paramedical fields.Reading Materials:References and Web links have been providedin all the modules.Learning Outcomes:After successful accomplishment of the course, the learners will be able to acquire better understanding and comprehensive knowledge regarding most of the essential aspects of Molecular Biology subject which in turn will provide a fantastic opportunity to develop professional skill related to the field of molecular biology.

Cell Biology

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Cell biology is an interdisciplinary subject integrating the fields of biochemistry, molecular cell biology and genetics. The aim of the course is to gives basic knowledge about the structure and function of cells and cellular components. The different modules of the course will examine different areas of cellular biology including structure and function of prokaryotic and eukaryotic cells, membrane and organelle structure and function, chemical composition of the cell, cell organelles and cellular communication. In this course, we will also examine the methods to fractionate cells and cellular components. The other important aspects of cell biology that will be discussed in the course includes: mechanisms behind organelle transport and secretion;; the structure and function of enzymes and kinetics of enzyme reactions; cell communication; intercellular contacts, cell surface receptors; extracellular matrices; signals over the plasma membrane, receptors, and cell signaling; the organisation and structure of the cell nucleus, chromatin and chromosomes.

Bioenergy

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This course aims to provide an overview of the basic process, by which solar energy is collected and converted to biomass, which is essentially, what we call ‘bioenergy’. During the discourse, emphasis will be given on different strategies to convert biomass to biofuels, the review of the available technologies and how these could meet the growing demand for energy in the future.INTENDED AUDIENCE: Bioengineers, Chemical engineers, Energy studies, Agriculturist, Policy makersPREREQUISITES: Has cleared 10+2 with scienceINDUSTRY SUPPORT : Green energy industries, Agro-waste processing industries, Renewable energy materials industry, Bio-fuel and fossil fuel companies.

Human Physiology

4.5

Human Physiology is the study of normal biological function from atoms to molecules, to cells to tissues, and to organs and organ systems. It is the integration of each of these elements that allows for the human body to function as a whole to accomplish particular tasks. In this course, we will focus on how the human body works through the activities of interconnected organ systems. We will begin by reviewing fundamental concepts from related fields of study including Chemistry, Molecular Biology, and Cell Biology. We will then build upon those concepts as we explore each of the organ systems, their interconnectivity and the effects that specific perturbations will have on those organ systems and subsequent ability to maintain homeostasis. Students will also apply their physiology knowledge to information they encounter on the Internet, in magazines, and on television. Students will complete this course using online resources including lecture videos, animations, workbooks, and discussions, followed by in-class activities that are designed to reinforce online activities and to promote critical thinking skills via case studies and clinical applications. The laboratory session will give students an appreciation of human physiology by conducting hands-on experiments that deal with principles discussed online and in-class.

General Microbiology

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Microbiology is the study of a diverse group of microscopic organisms such as bacteria, viruses, fungi and protozoa. They are generally too small to be seen without the use of microscope and hence these life forms are called the microorganisms or the microbes. They are almost everywhere and affect almost all aspects of our lives. This is a general microbiology course that is intended for students to impart the knowledge of microbial life. The course structure is based on presenting the fundamentals of microbiology i.e. the biology of bacteria, fungi, viruses and protozoa, their classification, bacterial genetics, mode of replication, bacterial photosynthesis, bacterial fermentation, microbial food spoilage and various methods of food preservation. The students will also be introduced to the microbial pathogenesis of various infectious agents that cause diseases in humans and prevention of the infection, host resistance and immunity etc. 

Bioenergetics of Life Processes

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Bioenergetics is a fundamental process in the evolution. The primitive self assembly of molecules to the supra-assembly of large polymers are govern by the basic laws of energetics. In this course, we will be discussing the basic energy harvesting processes which govern the self assembly of biomolecules and their utilization to generate energy to run the biological machinery of evolution.INTENDED AUDIENCE : Bioengineers, Chemical engineers, Energy studies, Agriculturist, Policy makersPRE-REQUISITES : 10+2 in scienceINDUSTRY SUPPORT : Bio-mimetics design, Solar panel development, Biosensor industry, Bio-electrochemical process industry

Introduction to Bioelectricity

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In this course you will use fundamental engineering and mathematical tools to understand and analyze basic bioelectricity and circuit theory in the context of the mammalian nervous system.This course is for students who are interested in learning about relating the systems of the human body that involve or communicate with bioelectrical systems, including the heart, brain, muscles, and the neuromuscular system that connects them all together. Students will learn how bioelectricity can be used to record and control the way the body electric behaves. Suggested text: “Neuroscience” by Purves, et al. This course is offered by the nanoHUB-U project, which is jointly funded by Purdue and NSF with the goal of transcending disciplines through short courses accessible to students in any branch of science or engineering. These courses focus on cutting-edge topics distilled into short lectures with quizzes, homework, and practice exams.

Моделирование биологических молекул на GPU (Biomolecular modeling on GPU)

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Class Central TipsLearn How to Sign up to Coursera courses for free1600+ Coursera Courses That Are Still Completely FreeС развитием компьютерной техники, вычислительный эксперимент стал неотъемлемой частью любого научного исследования. На сегодняшний день, компьютеры помогают решать целый спектр различных задач - от гидродинамики до макроэкономики. В исследованиях биологических молекул, вычислительный эксперимент закрепился сравнительно недавно. Виной тому - сложность структуры биомолекул, которые могут насчитывать сотни, тысячи или даже десятки, сотни тысяч атомов. Под словом "моделирование" в названии курса подразумевается как раз вычислительный эксперимент. В начале XXI века, благодаря появлению новой высокопараллельной аппаратной платформы - графических процессоров, вычислительный эксперимент получил новый виток развития. Решение множества вычислительных задач - хорошо параллелизуемо. То есть, различные части расчёта можно производить одновременно. Одной из таких задач является молекулярное моделирование.Цель данного курса - обеспечить понимание основных принципов молекулярного моделирования. В первой части пособия дан обзор строения различных биологических молекул - от последовательности до трёхмерной структуры. Далее разъяснены методы молекулярной механики и динамики, а также рассмотрены предпосылки использования различных подходов к моделированию. В качестве первого практического примера рассмотрена простая задача моделирования с применением общедоступного бесплатного пакета NAMD, разъяснены основы метода молекулярной динамики и использования программного пакета VMD для визуализации и анализа результатов. В последней части курса детально разобраны методы реализации численных методов молекулярного моделирования - как на центральном процессоре, так и на графическом. В курсе даётся вводная информация об устройстве ГП и его использовании для численных расчётов. Курс расчитан на студентов технических специальностей.В рамках курса, слушатели узнают основы строения биологических молекул, научатся искать и визуализировать их структуры. Навыки использования готовых программных пакетов для биомолекулярного моделирования позволят наблюдать за динамикой каждого атома биомолекулы. Знания используемого в молекулярном моделировании математического формализма помогут лучше понимать возможности и ограничения молекулярного моделирования. Основы языка CUDA для программирования на графических процессорах будут закреплены программная реализация простой задачи молекулярного моделирования.Данный курс будет интересен студентам технических специальностей, которые научатся применять уже имеющиеся у них знания в новой области. Студенты биолгических специальностей получат необходимые знания для применения вычислительного эксперимента в их деятельности.

La necropsia en los animales domésticos

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"La necropsia es una herramienta diagnóstica sobre animales muertos.El alumnoaprenderá a hacer la inspección externa, la apertura de las diferentes cavidades orgánicas de las distintas especies animales de interés veterinario, así como el procedimiento de extracción de las vísceras de los animales objeto de la necropsia.Posteriormente el alumno aprenderá como se inspeccionan las vísceras con el objeto de recoger los datos (lesiones) y de cómo se toman las muestras para estudios complementarios."

Mulberry and Silkworm Crop Protection

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Sericulture is practiced in more than 50 countries of the world under tropical and subtropical conditions. In India, it is a well established agro-based cottage industry with greater employment opportunities in rural areas. India enjoys a dubious distinction of being the only country producing all the five commercially known silks, viz. mulberry, tropical tasar, temperate or oak tasar, eri and muga. Among these, mulberry silk alone accounts for about 90% of the raw silk produced in the country. Mulberry sericulture chiefly comprises four distinct activities, viz. mulberry cultivation, silkworm rearing, silkworm egg production as well as silk reeling and silk weaving. Of these, mulberry cultivation and silkworm rearing form the basis for rest of the activities and contribute greatly to ultimate and determine the profitability.Mulberry (Morus spp.) constitutes the exclusive food plant of the silkworm, Bombyx mori. Hence, production of an appreciable quantity of superior quality mulberry foliage assumes great significance in order to realize silkworm rearing a profitable venture. Some of the major constraints in this regard includes lack of irrigation, insufficient rainfall, unscientific agronomical practices and outbreak of diseases and pests. The diseases of mulberry are caused by fungi, bacteria, nematodes, mycoplasma and viruses and account for a reduction of 12-15% in leaf production apart from considerable decline in quality. Similarly, the pests cause a reduction of 10-15% in leaf yield in addition to sizeable lowering of quality. With regard to silkworm diseases caused by protozoa, bacteria, viruses and fungi. The loss in cocoon yield is of the order of 10-15% with considerable reduction in silk quantity. Likewise the pests, chiefly the uzi fly, Exorista bombycis inflict a reduction of 10-20% in cocoon yield. On the whole, the pests and diseases of mulberry and silkworm constitute the major impediments that cause considerable economic loss. Therefore, there isan dire need to sericulture farmers to take up appropriate measures to alleviate the problems in question in order to realize the desired benefits.The course helps us to understand the technologies and package of practices for mulberry and silkworm diseases and management of insect pests. This will aid in developing of forewarning systems, disease monitoring system to individuals involved in mulberry cultivation, silkworm seed multiplication and rearing of silkworms. Also maintain, multiply and supply of bio-control agents to control the insect pests of host plant and silkworm with evaluation and management strategies for prevention and control. Study and understanding of the therapeutic control of fungal, viral and bacterial diseases of silkworm along with the other factors responsible for crop losses. This knowledge can be used in enhancing the productivity of mulberry and silkworm both qualitatively and quantitatively

BioMEMS And Microfluidics

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During the last several decades, micro-system research mainly addressed electromechanical systems and in recent years, the focus has shifted to Bio-Microelectromechanical Systems (BioMEMS). This shift is driven primarily by the potential applications of the micro-systems to chemistry, biology and medicine. In fact, a combination of BioMEMS and microsystems has made possible the realization of physical systems at scales and dimensions similar to biological entities such as bacterial and mammalian cells, viruses, spores, etc., and this has resulted in the development of a variety of diagnostic and therapeutic applications, intelligent biochips and sensors. BioMEMS today finds many applications within the chemical, health-care, biotechnological and manufacturing industries and this has necessitated a considerable shift in the focus of engineering education. This course illustrates a post graduate level introductory course in BioMEMS and micro-systems.INTENDED AUDIENCEThis course would be relevant for mechanical engineering manufacturing science/ fluidic streams graduate students and some senior undergraduate students. The interdisciplinary nature of the course would also be able to attract students from various disciplines like biosciences/ bioengineering, chemical engineering and environmental engineering. (Refer to participating faculty list). A considerable portion of the material will also be directly taught from review articles and publications. The highly interdisciplinary nature and research focus of this course may eventually be able attract some undergraduate students into graduate programs.PREREQUISITES:Chemistry and basic fluid mechanicsINDUSTRY SUPPORT: Nil

Plant groups

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The CC- Botany 1 entitled Plant Groups is actually a course on basic plant diversity and comprises of 40 modules. It gives a detailed account of different plant groups like virus, bacteria, algae, fungi including and mycorrhizae, archegoniates including bryophytes, pteridophytes and also the spermatophyte in the form gymnosperms. Each group have detailed discussion of their classification, ecological importance, classification and phylogeny, certain important type genera and also their economic importance. Thus by studying these 40 modules, a student should be able to understand and appreciate the major plant groups from microbes to gymnosperms which form the basis of plant sciences. Students from any branch of biological sciences will find these modules relevant and useful for their higher studies.