The Immune System: New Developments in Research - Part 1

WEEK1:  Overview of Immunology

• What is the immune system?
• Players act in the immune system
• How various types of immune cells work in the immune system?

 
WEEK2:  Innate Immunity
2-1:  Innate Immunity- Pathogen Recognition by Innate Immunity

• Mechanism of innate immunity
• Interaction between innate immunity and adaptive immunity

Pattern recognition receptors
2-2:  Innate Immunity - Disorder-specific M2 Macrophages

• Functions of macrophages
• Recent topics in the research for various types of M2 macrophages

2-3:  Innate Immunity - Understanding and Manipulation of the NLRP3-inflammasome

• Colchicine inhibits activation of the NLRP3-inflammasome
• Autophagy limits activation of the NLRP3-inflammasome

 
WEEK 3: Adaptive Immunity 1 - Control of Immune Responses by Regulatory T Cells

• Identification of regulatory T (Treg) cells
• FoxP3 is a Treg specific transcription factor, and it controls IL-2 production
• Treg-targeting cancer immunotherapy

 
WEEK 4: Adaptive Immunity 2
4-1:  Adaptive Immunity 2 - Immune Regulatory Mechanisms through B Cell Axis
Anti-inflammatory functions by B cell

• Regulatory function of plasmablasts to suppress Experimental Autoimmune Encephalomyelitis (EAE)
• Essential signaling factors in B cells for IL-10 production

4-2:  Adaptive Immunity 2 - Vaccine & Immunological Memory

• What is vaccine (vaccination)?
• What is immunological memory?
• What are the issues in the research for immunological memory?

 
WEEK 5: Mucosal Immunology

• Barrier functions of epithelial cells
• Intestinal environmental factors
• Unique immune cells in the intestinal mucosa